Is tamoxifen a steroid

Discussion in 'Canadian Pharmacy Meds' started by Keysee, 04-Sep-2019.

  1. morphru Well-Known Member

    Is tamoxifen a steroid


    In 2006, the large STAR clinical study concluded that raloxifene is equally effective in reducing the incidence of breast cancer, but after an average 4-year follow-up, although the difference was not statistically significant, there were 36% fewer uterine cancers and 29% fewer blood clots in women taking raloxifene than in women taking tamoxifen. Tamoxifen improves fertility in males with infertility by disinhibiting the hypothalamic–pituitary–gonadal axis (HPG axis) via ER antagonism and thereby increasing the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) and increasing testicular testosterone production. It is taken as a preventative measure in small doses, or used at the onset of any symptoms such as nipple soreness or sensitivity. Other drugs are taken for similar purposes such as clomifene and the anti-aromatase drugs which are used in order to try to avoid the hormone-related adverse effects. Occasionally tamoxifen is used in treatment of the rare conditions of retroperitoneal fibrosis A report in September 2009 from Health and Human Services' Agency for Healthcare Research and Quality suggests that tamoxifen, raloxifene, and tibolone used to treat breast cancer significantly reduce invasive breast cancer in midlife and older women, but also increase the risk of adverse side effects. Some cases of lower-limb lymphedema have been associated with the use of tamoxifen, due to the blood clots and deep vein thrombosis (DVT) that can be caused by this medication. Resolution of the blood clots or DVT is needed before lymphedema treatment can be initiated. – A concern about anabolic steroid use is the resulting suppression of natural testosterone production. During an anabolic steroid cycle itself, this suppression is unavoidable and isn’t necessarily a problem. However, extended post-cycle suppression results in loss of gains and can result in adverse side effects such as depression and loss of libido. In contrast, where recovery of natural testosterone production is rapid, adverse effects on mood or libido can be reduced or eliminated, and retention of gains can be excellent. Post-cycle therapy (PCT) with Nolvadex was introduced specifically to enable faster recovery. To understand how Nolvadex can speed recovery, it’s important to understand how inhibition occurs, and how it may be reversed by a selective estrogen receptor modulator (SERM) such as Nolvadex. Testosterone production is regulated in a chain process.

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    Effects of tamoxifen on steroid hormone receptors and hormone concentration and the results of DNA analysis by flow cytometry in endometrial carcinoma. By using tamoxifen, abusers of anabolic steroids are trying to prevent the estrogenic harm caused by anabolic steroids, such as the overgrowth of breasts. Nolvadex also has some highly important and practical roles for a steroid using athlete who is coming off a cycle. Hypogonadic and infertile men given Nolvadex, saw significant increases in the serum levels of LH, FSH, as well as testosterone levels 3 4.

    Tamoxifen Citrate is a Selective Estrogen Receptor Modulator (SERM), often referred to as an anti-estrogen. It acts as an anti-estrogen in certain areas of the body while acting as an estrogen in other areas. Even though it is used by many anabolic steroid users used during steroid use to help with estrogenic related side effects, it is most commonly used during Post Cycle Therapy (PCT). Post Cycle Therapy (PCT) is the 3-6 week period following steroid use implemented to help with natural testosterone production. Tamoxifen Citrate prevents the estrogen from binding. It won’t help with water retention or gynecomastia for all men, but that depends on how high estrogen levels go as well as genetics. If more or stronger protection is needed, Aromatase Inhibitors (AI’s) are recommended. Nolvadex is a popular and powerfully effective Selective Estrogen Receptor Modulator (SERM) that is often referred to as an anti-estrogen. However, while being an antagonist it is also an agonist as it will actually act as estrogen in certain parts of the body while acting as an anti-estrogen in other areas. As one of the oldest SERM’s on the market that is still regularly used medicinally, while Nolvadex is also used by anabolic steroid users it is not an anabolic steroid. This is an important note as some are often confused by its use in steroid cycles. Nolvadex, officially known as Tamoxifen Citrate, was first developed in 1961 by ICI now Astra Zeneca under the trade name Nolvadex. The SERM was developed to treat breast cancer, specifically hormone-responsive breast cancer. However, it has also been effectively used in breast cancer prevention. Then we have anabolic steroid users, and it was long ago discovered that Nolvadex had a place among such individuals.

    Is tamoxifen a steroid

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    Is tamoxifen a steroid - The most quality treatments manufactured by the leading manufacturers are offered in the pharmacy High confidentiality level and privacy. The study also found a 22% rise in the numbers using tamoxifen, and the. Prof Davies added that many steroid abusers were not injecting the. Once steroid use is complete, Tamoxifen can speed up the testosterone production. Tamoxifen administration For on cycle gynecomastia prevention, 10-20mg per day is the standard range.

     
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