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Common Questions and Answers about Tadalafil half life cialis There are many other good products in the market for half of the price like generic Cialis Tadalafil, generic Viagra Sildenafil, generic Levitra Vardenafil, Dapoxetine and Kamagra that work just as well depending on someone's preference. Feb 18, 2019. Quick easy-to-read overview of Cialis. Includes how it works, upsides, downsides, bottom line, tips, response and effectiveness. Known also as the 'weekend pill', the durable half-life of Cialis 17.5 hours, making it active for up to 36 hours sets it apart from those treatments with a shorter.